Are there nonstop flights from San Diego (SAN) to Louisville (SDF)?

No. The fastest connection is via Phoenix, about 4h 26m of total flying time.

What is the fastest connection from San Diego (SAN) to Louisville (SDF)?

via Phoenix ≈ 4h 26m, via Denver ≈ 4h 33m, via Las Vegas ≈ 4h 33m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 15,000 JAL miles (economy, one way, based on the published award charts).

San Diego International Airport (SAN) to Louisville Muhammad Ali International Airport (SDF)・2,898 km

No nonstop flights. The fastest connection is via Phoenix (PHX), about 4h 26m of flying time (layover not included).

With milesANA 15,000 miles+ (via DEN)JAL 15,000 miles+ (via DFW)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

29 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.