Are there nonstop flights from San Diego (SAN) to Portland (PWM)?

No. The fastest connection is via Chicago, about 5h 57m of total flying time.

What is the fastest connection from San Diego (SAN) to Portland (PWM)?

via Chicago ≈ 5h 57m, via Chicago ≈ 5h 57m, via Detroit ≈ 5h 58m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 23,000 JAL miles (economy, one way, based on the published award charts).

San Diego International Airport (SAN) to Portland International Jetport (PWM)・4,212 km

No nonstop flights. The fastest connection is via Chicago (ORD), about 5h 57m of flying time (layover not included).

With milesANA 15,000 miles+ (via ORD)JAL 23,000 miles+ (via PHL)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

25 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.