Are there nonstop flights from San Diego (SAN) to São Paulo (GRU)?

No. The fastest connection is via Panama City, about 12h 30m of total flying time.

What is the fastest connection from San Diego (SAN) to São Paulo (GRU)?

via Panama City ≈ 12h 30m, via Houston ≈ 12h 46m, via Los Angeles ≈ 12h 52m (estimated flying time, excluding layovers).

from 30,000 ANA miles, from 40,000 JAL miles (economy, one way, based on the published award charts).

San Diego International Airport (SAN) to São Paulo/Guarulhos–Governor André Franco Montoro International Airport (GRU)・9,754 km

No nonstop flights. The fastest connection is via Panama City (PTY), about 12h 30m of flying time (layover not included).

With milesANA 30,000 miles+ (via PTY)JAL 40,000 miles+ (via DFW)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

17 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.