Are there nonstop flights from San Salvador (SAL) to Des Moines (DSM)?

No. The fastest connection is via Houston, about 4h 49m of total flying time.

What is the fastest connection from San Salvador (SAL) to Des Moines (DSM)?

via Houston ≈ 4h 49m, via Dallas-Fort Worth ≈ 4h 54m, via Atlanta ≈ 5h 6m (estimated flying time, excluding layovers).

from 23,000 JAL miles, from 30,000 ANA miles (economy, one way, based on the published award charts).

El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez (SAL) to Des Moines International Airport (DSM)・3,155 km

No nonstop flights. The fastest connection is via Houston (IAH), about 4h 49m of flying time (layover not included).

With milesJAL 23,000 miles+ (via DFW)ANA 30,000 miles+ (via IAH)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

10 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.