Are there nonstop flights from Fort Myers (RSW) to Key West (EYW)?

No. The fastest connection is via Orlando, about 1h 46m of total flying time.

What is the fastest connection from Fort Myers (RSW) to Key West (EYW)?

via Orlando ≈ 1h 46m (estimated flying time, excluding layovers).

Southwest Florida International Airport (RSW) to Key West International Airport (EYW)・220 km

No nonstop flights. The fastest connection is via Orlando (MCO), about 1h 46m of flying time (layover not included).

None.

1 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.