Are there nonstop flights from Fort Myers (RSW) to Wilkes-Barre/Scranton (AVP)?

Yes. Breeze Airways fly this route. Flight time is about 2h 33m.

What is the fastest connection from Fort Myers (RSW) to Wilkes-Barre/Scranton (AVP)?

via Orlando ≈ 3h 2m, via Washington ≈ 3h 2m, via Philadelphia ≈ 3h 5m (estimated flying time, excluding layovers).

from 15,000 JAL miles (economy, one way, based on the published award charts).

Southwest Florida International Airport (RSW) to Wilkes-Barre/Scranton International Airport (AVP)・1,736 km

Nonstop flights available (1 airline). Flight time about 2h 33m. Nonstop return flights also operate.

With milesJAL 15,000 miles+ (via PHL)Economy, one way, estimate. Tap a connection for miles by cabin.

5 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.