Are there nonstop flights from Rochester (ROC) to Panama City (PTY)?

No. The fastest connection is via Raleigh/Durham, about 5h 27m of total flying time.

What is the fastest connection from Rochester (ROC) to Panama City (PTY)?

via Raleigh/Durham ≈ 5h 27m, via Washington ≈ 5h 28m, via Miami ≈ 5h 28m (estimated flying time, excluding layovers).

from 30,000 ANA miles (economy, one way, based on the published award charts).

Frederick Douglass Greater Rochester International Airport (ROC) to Tocumen International Airport (PTY)・3,790 km

No nonstop flights. The fastest connection is via Raleigh/Durham (RDU), about 5h 27m of flying time (layover not included).

With milesANA 30,000 miles+ (via ORD)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

12 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.