Are there nonstop flights from Rochester (ROC) to Istanbul (IST)?

No. The fastest connection is via Boston, about 10h 44m of total flying time.

What is the fastest connection from Rochester (ROC) to Istanbul (IST)?

via Boston ≈ 10h 44m, via Newark ≈ 10h 56m, via New York ≈ 10h 57m (estimated flying time, excluding layovers).

from 27,500 ANA miles (economy, one way, based on the published award charts).

Frederick Douglass Greater Rochester International Airport (ROC) to İstanbul Airport (IST)・8,093 km

No nonstop flights. The fastest connection is via Boston (BOS), about 10h 44m of flying time (layover not included).

With milesANA 27,500 miles+ (via ORD)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

8 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.