Are there nonstop flights from Portland (PWM) to Rochester (ROC)?

No. The fastest connection is via New York, about 2h of total flying time.

What is the fastest connection from Portland (PWM) to Rochester (ROC)?

via New York ≈ 2h, via Newark ≈ 2h, via New York ≈ 2h 1m (estimated flying time, excluding layovers).

Portland International Jetport (PWM) to Frederick Douglass Greater Rochester International Airport (ROC)・598 km

No nonstop flights. The fastest connection is via New York (LGA), about 2h of flying time (layover not included).

None.

8 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.