Are there nonstop flights from Portland (PWM) to New Orleans (MSY)?

No. The fastest connection is via Washington, about 3h 44m of total flying time.

What is the fastest connection from Portland (PWM) to New Orleans (MSY)?

via Washington ≈ 3h 44m, via Baltimore ≈ 3h 44m, via Washington ≈ 3h 45m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 15,000 JAL miles (economy, one way, based on the published award charts).

Portland International Jetport (PWM) to Louis Armstrong New Orleans International Airport (MSY)・2,326 km

No nonstop flights. The fastest connection is via Washington (IAD), about 3h 44m of flying time (layover not included).

With milesANA 15,000 miles+ (via IAD)JAL 15,000 miles+ (via DCA)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

25 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.