Are there nonstop flights from Portland (PWM) to Reykjavík (KEF)?

No. The fastest connection is via New York, about 6h 25m of total flying time.

What is the fastest connection from Portland (PWM) to Reykjavík (KEF)?

via New York ≈ 6h 25m, via Newark ≈ 6h 27m, via Baltimore ≈ 7h 4m (estimated flying time, excluding layovers).

from 27,500 ANA miles (economy, one way, based on the published award charts).

Portland International Jetport (PWM) to Keflavik International Airport (KEF)・3,725 km

No nonstop flights. The fastest connection is via New York (JFK), about 6h 25m of flying time (layover not included).

With milesANA 27,500 miles+ (via EWR)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

11 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.