Are there nonstop flights from Portland (PWM) to Cairo (CAI)?

No. The fastest connection is via New York, about 12h 7m of total flying time.

What is the fastest connection from Portland (PWM) to Cairo (CAI)?

via New York ≈ 12h 7m, via Newark ≈ 12h 10m, via Washington ≈ 12h 58m (estimated flying time, excluding layovers).

from 35,000 ANA miles (economy, one way, based on the published award charts).

Portland International Jetport (PWM) to Cairo International Airport (CAI)・8,599 km

No nonstop flights. The fastest connection is via New York (JFK), about 12h 7m of flying time (layover not included).

With milesANA 35,000 miles+ (via EWR)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

5 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.