Are there nonstop flights from Punta Cana (PUJ) to Quito (UIO)?

Yes. Arajet, Avianca Ecuador fly this route. Flight time is about 3h 16m.

What is the fastest connection from Punta Cana (PUJ) to Quito (UIO)?

via Medellín ≈ 3h 45m, via Bogota ≈ 3h 48m, via Panama City ≈ 4h 5m (estimated flying time, excluding layovers).

from 17,500 ANA miles, from 23,000 JAL miles (economy, one way, based on the published award charts).

Punta Cana International Airport (PUJ) to Mariscal Sucre International Airport (UIO)・2,348 km

Nonstop flights available (2 airlines). Flight time about 3h 16m. Nonstop return flights also operate.

With milesANA 17,500 miles+ (via BOG)JAL 23,000 miles+ (via MIA)Economy, one way, estimate. Tap a connection for miles by cabin.

7 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.