Are there nonstop flights from Punta Cana (PUJ) to Santiago (SCU)?

No. The fastest connection is via Port-au-Prince, about 1h 57m of total flying time.

What is the fastest connection from Punta Cana (PUJ) to Santiago (SCU)?

via Port-au-Prince ≈ 1h 57m, via Kingston ≈ 2h 21m, via Willemstad ≈ 3h 10m (estimated flying time, excluding layovers).

Punta Cana International Airport (PUJ) to Antonio Maceo International Airport (SCU)・800 km

No nonstop flights. The fastest connection is via Port-au-Prince (PAP), about 1h 57m of flying time (layover not included).

None.

3 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.