Are there nonstop flights from Panama City (PTY) to St Louis (STL)?

No. The fastest connection is via Tampa, about 5h 9m of total flying time.

What is the fastest connection from Panama City (PTY) to St Louis (STL)?

via Tampa ≈ 5h 9m, via Cancún ≈ 5h 11m, via Atlanta ≈ 5h 11m (estimated flying time, excluding layovers).

from 23,000 JAL miles, from 30,000 ANA miles (economy, one way, based on the published award charts).

Tocumen International Airport (PTY) to St. Louis Lambert International Airport (STL)・3,477 km

No nonstop flights. The fastest connection is via Tampa (TPA), about 5h 9m of flying time (layover not included).

With milesJAL 23,000 miles+ (via MIA)ANA 30,000 miles+ (via IAH)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

24 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.