Are there nonstop flights from Panama City (PTY) to Singapore (SIN)?

No. The fastest connection is via Newark, about 23h 14m of total flying time.

What is the fastest connection from Panama City (PTY) to Singapore (SIN)?

via Newark ≈ 23h 14m, via New York ≈ 23h 14m, via San Francisco ≈ 23h 16m (estimated flying time, excluding layovers).

from 55,000 JAL miles, from 67,500 ANA miles (economy, one way, based on the published award charts).

Tocumen International Airport (PTY) to Singapore Changi Airport (SIN)・18,797 km

No nonstop flights. The fastest connection is via Newark (EWR), about 23h 14m of flying time (layover not included).

With milesJAL 55,000 miles+ (via CDG)ANA 67,500 miles+ (via EWR)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

8 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.