Are there nonstop flights from Panama City (PTY) to Louisville (SDF)?

No. The fastest connection is via Atlanta, about 4h 53m of total flying time.

What is the fastest connection from Panama City (PTY) to Louisville (SDF)?

via Atlanta ≈ 4h 53m, via Tampa ≈ 4h 53m, via Orlando ≈ 4h 55m (estimated flying time, excluding layovers).

from 23,000 JAL miles, from 30,000 ANA miles (economy, one way, based on the published award charts).

Tocumen International Airport (PTY) to Louisville Muhammad Ali International Airport (SDF)・3,298 km

No nonstop flights. The fastest connection is via Atlanta (ATL), about 4h 53m of flying time (layover not included).

With milesJAL 23,000 miles+ (via MIA)ANA 30,000 miles+ (via DEN)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

13 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.