Are there nonstop flights from Panama City (PTY) to Johannesburg (JNB)?

No. The fastest connection is via São Paulo, about 15h 44m of total flying time.

What is the fastest connection from Panama City (PTY) to Johannesburg (JNB)?

via São Paulo ≈ 15h 44m, via Madrid ≈ 20h 8m, via Atlanta ≈ 20h 15m (estimated flying time, excluding layovers).

from 34,000 ANA miles, from 50,000 JAL miles (economy, one way, based on the published award charts).

Tocumen International Airport (PTY) to O.R. Tambo International Airport (JNB)・12,204 km

No nonstop flights. The fastest connection is via São Paulo (GRU), about 15h 44m of flying time (layover not included).

With milesANA 34,000 miles+ (via GRU)JAL 50,000 miles+ (via CDG)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

7 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.