Are there nonstop flights from Panama City (PTY) to Rome (FCO)?

No. The fastest connection is via Madrid, about 12h 10m of total flying time.

What is the fastest connection from Panama City (PTY) to Rome (FCO)?

via Madrid ≈ 12h 10m, via Paris ≈ 12h 29m, via Amsterdam ≈ 12h 54m (estimated flying time, excluding layovers).

from 35,000 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

Tocumen International Airport (PTY) to Rome–Fiumicino Leonardo da Vinci International Airport (FCO)・9,471 km

No nonstop flights. The fastest connection is via Madrid (MAD), about 12h 10m of flying time (layover not included).

With milesANA 35,000 miles+ (via EWR)JAL 37,000 miles+ (via MAD)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

24 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.