Are there nonstop flights from Portsmouth (PSM) to Fort Myers (RSW)?

Yes. Breeze Airways fly this route. Flight time is about 2h 57m.

What is the fastest connection from Portsmouth (PSM) to Fort Myers (RSW)?

via Orlando ≈ 3h 28m, via Raleigh/Durham ≈ 3h 30m (estimated flying time, excluding layovers).

Portsmouth International Airport at Pease (PSM) to Southwest Florida International Airport (RSW)・2,088 km

Nonstop flights available (1 airline). Flight time about 2h 57m. Nonstop return flights also operate.

2 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.