Are there nonstop flights from Prague (PRG) to Vilnius (VNO)?

Yes. Wizz Air fly this route. Flight time is about 1h 34m.

What is the fastest connection from Prague (PRG) to Vilnius (VNO)?

via Warsaw ≈ 2h 5m, via Gdańsk ≈ 2h 10m, via Kraków ≈ 2h 12m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 15,000 JAL miles (economy, one way, based on the published award charts).

Václav Havel Airport Prague (PRG) to Vilnius International Airport (VNO)・901 km

Nonstop flights available (1 airline). Flight time about 1h 34m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via WAW)JAL 15,000 miles+ (via HEL)Economy, one way, estimate. Tap a connection for miles by cabin.

26 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.