Are there nonstop flights from Prague (PRG) to Tenerife (TFS)?

Yes. Eurowings, Smartwings fly this route. Flight time is about 4h 42m.

What is the fastest connection from Prague (PRG) to Tenerife (TFS)?

via Madrid ≈ 5h 12m, via Lyon ≈ 5h 12m, via Geneva ≈ 5h 12m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 23,000 JAL miles (economy, one way, based on the published award charts).

Václav Havel Airport Prague (PRG) to Tenerife Sur Airport (TFS)・3,573 km

Nonstop flights available (2 airlines). Flight time about 4h 42m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via LIS)JAL 23,000 miles+ (via CDG)Economy, one way, estimate. Tap a connection for miles by cabin.

78 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.