Are there nonstop flights from Prague (PRG) to Sta Cruz de la Palma (SPC)?

Yes. Smartwings fly this route. Flight time is about 4h 44m.

What is the fastest connection from Prague (PRG) to Sta Cruz de la Palma (SPC)?

via Madrid ≈ 5h 13m, via Basel / Mulhouse ≈ 5h 14m, via Zurich ≈ 5h 14m (estimated flying time, excluding layovers).

from 23,000 JAL miles (economy, one way, based on the published award charts).

Václav Havel Airport Prague (PRG) to La Palma Airport (SPC)・3,595 km

Nonstop flights available (1 airline). Flight time about 4h 44m. Nonstop return flights also operate.

With milesJAL 23,000 miles+ (via MAD)Economy, one way, estimate. Tap a connection for miles by cabin.

17 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.