Are there nonstop flights from Prague (PRG) to Poznań (POZ)?

Yes. Ryanair fly this route. Flight time is about 52m.

What is the fastest connection from Prague (PRG) to Poznań (POZ)?

via Kraków ≈ 1h 51m, via Warsaw ≈ 1h 57m, via Munich ≈ 2h (estimated flying time, excluding layovers).

from 15,000 ANA miles (economy, one way, based on the published award charts).

Václav Havel Airport Prague (PRG) to Poznań-Ławica Airport (POZ)・314 km

Nonstop flights available (1 airline). Flight time about 52m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via WAW)Economy, one way, estimate. Tap a connection for miles by cabin.

5 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.