Are there nonstop flights from Prague (PRG) to Johannesburg (JNB)?

No. The fastest connection is via Munich, about 11h 15m of total flying time.

What is the fastest connection from Prague (PRG) to Johannesburg (JNB)?

via Munich ≈ 11h 15m, via Cairo ≈ 11h 29m, via Zurich ≈ 11h 30m (estimated flying time, excluding layovers).

from 30,000 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

Václav Havel Airport Prague (PRG) to O.R. Tambo International Airport (JNB)・8,589 km

No nonstop flights. The fastest connection is via Munich (MUC), about 11h 15m of flying time (layover not included).

With milesANA 30,000 miles+ (via MUC)JAL 37,000 miles+ (via CDG)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

12 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.