Are there nonstop flights from Prague (PRG) to Alicante (ALC)?

Yes. easyJet, Eurowings fly this route. Flight time is about 2h 34m.

What is the fastest connection from Prague (PRG) to Alicante (ALC)?

via Marseille ≈ 3h 4m, via Munich ≈ 3h 5m, via Barcelona ≈ 3h 5m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 15,000 JAL miles (economy, one way, based on the published award charts).

Václav Havel Airport Prague (PRG) to Alicante-Elche Miguel Hernández Airport (ALC)・1,761 km

Nonstop flights available (2 airlines). Flight time about 2h 34m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via ZRH)JAL 15,000 miles+ (via MAD)Economy, one way, estimate. Tap a connection for miles by cabin.

77 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.