Are there nonstop flights from Palermo (PMO) to Minneapolis (MSP)?

No. The fastest connection is via Dublin, about 10h 42m of total flying time.

What is the fastest connection from Palermo (PMO) to Minneapolis (MSP)?

via Dublin ≈ 10h 42m, via Paris ≈ 10h 42m, via London ≈ 10h 43m (estimated flying time, excluding layovers).

from 27,500 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

Falcone–Borsellino Airport (PMO) to Minneapolis–Saint Paul International Airport / Wold–Chamberlain Field (MSP)・8,202 km

No nonstop flights. The fastest connection is via Dublin (DUB), about 10h 42m of flying time (layover not included).

With milesANA 27,500 miles+ (via EWR)JAL 37,000 miles+ (via CDG)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

8 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.