Are there nonstop flights from Providenciales (PLS) to Santiago (STI)?

Yes. InterCaribbean Airways, Caicos Express Airways fly this route. Flight time is about 52m.

Providenciales → Santiago

Providenciales International Airport (PLS) to Cibao International Airport (STI)・315 km

Nonstop flights available (2 airlines). Flight time about 52m. Nonstop return flights also operate.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.