Are there nonstop flights from Paphos (PFO) to Madrid (MAD)?

No. The fastest connection is via Mykonos, about 4h 47m of total flying time.

What is the fastest connection from Paphos (PFO) to Madrid (MAD)?

via Mykonos ≈ 4h 47m, via Athens ≈ 4h 48m, via Naples ≈ 4h 48m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 23,000 JAL miles (economy, one way, based on the published award charts).

Paphos International Airport (PFO) to Adolfo Suárez Madrid–Barajas Airport (MAD)・3,217 km

No nonstop flights. The fastest connection is via Mykonos (JMK), about 4h 47m of flying time (layover not included).

With milesANA 15,000 miles+ (via ATH)JAL 23,000 miles+ (via AMM)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

43 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.