Are there nonstop flights from Chicago (ORD) to Thessaloniki (SKG)?

No. The fastest connection is via Brussels, about 11h of total flying time.

What is the fastest connection from Chicago (ORD) to Thessaloniki (SKG)?

via Brussels ≈ 11h, via Dublin ≈ 11h, via London ≈ 11h 1m (estimated flying time, excluding layovers).

from 27,500 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

Chicago O'Hare International Airport (ORD) to Thessaloniki Macedonia International Airport (SKG)・8,508 km

No nonstop flights. The fastest connection is via Brussels (BRU), about 11h of flying time (layover not included).

With milesANA 27,500 miles+ (via BRU)JAL 37,000 miles+ (via LHR)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

24 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.