Are there nonstop flights from Porto (OPO) to Santiago (SCL)?

No. The fastest connection is via Recife, about 13h 38m of total flying time.

What is the fastest connection from Porto (OPO) to Santiago (SCL)?

via Recife ≈ 13h 38m, via São Paulo ≈ 13h 42m, via Rio De Janeiro ≈ 13h 49m (estimated flying time, excluding layovers).

from 35,000 ANA miles, from 45,000 JAL miles (economy, one way, based on the published award charts).

Francisco de Sá Carneiro Airport (OPO) to Comodoro Arturo Merino Benítez International Airport (SCL)・10,449 km

No nonstop flights. The fastest connection is via Recife (REC), about 13h 38m of flying time (layover not included).

With milesANA 35,000 miles+ (via GRU)JAL 45,000 miles+ (via MAD)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

11 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.