Are there nonstop flights from Nantes (NTE) to Brussels (BRU)?

Yes. easyJet fly this route. Flight time is about 1h 13m.

What is the fastest connection from Nantes (NTE) to Brussels (BRU)?

via Paris ≈ 1h 44m, via Amsterdam ≈ 2h 3m, via Frankfurt am Main ≈ 2h 18m (estimated flying time, excluding layovers).

from 15,000 ANA miles (economy, one way, based on the published award charts).

Nantes Atlantique Airport (NTE) to Brussels Airport (BRU)・609 km

Nonstop flights available (1 airline). Flight time about 1h 13m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via FRA)Economy, one way, estimate. Tap a connection for miles by cabin.

13 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.