Are there nonstop flights from Naples (NAP) to Charlotte (CLT)?

No. The fastest connection is via Rome, about 10h 19m of total flying time.

What is the fastest connection from Naples (NAP) to Charlotte (CLT)?

via Rome ≈ 10h 19m, via New York ≈ 10h 20m, via Philadelphia ≈ 10h 20m (estimated flying time, excluding layovers).

from 27,500 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

Naples International Airport (NAP) to Charlotte Douglas International Airport (CLT)・7,925 km

No nonstop flights. The fastest connection is via Rome (FCO), about 10h 19m of flying time (layover not included).

With milesANA 27,500 miles+ (via EWR)JAL 37,000 miles+ (via PHL)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

14 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.