Are there nonstop flights from Myrtle Beach (MYR) to São Paulo (GRU)?

No. The fastest connection is via Orlando, about 9h 49m of total flying time.

What is the fastest connection from Myrtle Beach (MYR) to São Paulo (GRU)?

via Orlando ≈ 9h 49m, via Atlanta ≈ 10h 26m, via Washington ≈ 10h 42m (estimated flying time, excluding layovers).

from 30,000 ANA miles, from 45,000 JAL miles (economy, one way, based on the published award charts).

Myrtle Beach International Airport (MYR) to São Paulo/Guarulhos–Governor André Franco Montoro International Airport (GRU)・7,220 km

No nonstop flights. The fastest connection is via Orlando (MCO), about 9h 49m of flying time (layover not included).

With milesANA 30,000 miles+ (via IAD)JAL 45,000 miles+ (via DFW)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

7 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.