Are there nonstop flights from Milan (MXP) to Pantelleria (PNL)?

No. The fastest connection is via Trapani, about 2h 13m of total flying time.

What is the fastest connection from Milan (MXP) to Pantelleria (PNL)?

via Trapani ≈ 2h 13m, via Rome ≈ 2h 15m, via Palermo ≈ 2h 17m (estimated flying time, excluding layovers).

Milan Malpensa International Airport (MXP) to Pantelleria Airport (PNL)・1,017 km

No nonstop flights. The fastest connection is via Trapani (TPS), about 2h 13m of flying time (layover not included).

None.

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5 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.