Are there nonstop flights from Milan (MXP) to Madison (MSN)?

No. The fastest connection is via Chicago, about 9h 44m of total flying time.

What is the fastest connection from Milan (MXP) to Madison (MSN)?

via Chicago ≈ 9h 44m, via Boston ≈ 9h 58m, via Newark ≈ 10h 4m (estimated flying time, excluding layovers).

from 27,500 ANA miles (economy, one way, based on the published award charts).

Milan Malpensa International Airport (MXP) to Dane County Regional Truax Field (MSN)・7,266 km

No nonstop flights. The fastest connection is via Chicago (ORD), about 9h 44m of flying time (layover not included).

With milesANA 27,500 miles+ (via ORD)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

6 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.