Are there nonstop flights from Milan (MXP) to Niš (INI)?

No. The fastest connection is via Belgrade, about 2h 19m of total flying time.

What is the fastest connection from Milan (MXP) to Niš (INI)?

via Belgrade ≈ 2h 19m, via Vienna ≈ 2h 33m, via Zurich ≈ 2h 34m (estimated flying time, excluding layovers).

from 15,000 ANA miles (economy, one way, based on the published award charts).

Milan Malpensa International Airport (MXP) to Niš Constantine the Great Airport (INI)・1,071 km

No nonstop flights. The fastest connection is via Belgrade (BEG), about 2h 19m of flying time (layover not included).

With milesANA 15,000 miles+ (via ZRH)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

9 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.