Are there nonstop flights from Milan (MXP) to São Paulo (GRU)?

Yes. LATAM Brasil fly this route. Flight time is about 11h 40m.

What is the fastest connection from Milan (MXP) to São Paulo (GRU)?

via Casablanca ≈ 12h 9m, via Barcelona ≈ 12h 10m, via Madrid ≈ 12h 12m (estimated flying time, excluding layovers).

from 35,000 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

Milan Malpensa International Airport (MXP) to São Paulo/Guarulhos–Governor André Franco Montoro International Airport (GRU)・9,485 km

Nonstop flights available (1 airline). Flight time about 11h 40m. Nonstop return flights also operate.

With milesANA 35,000 miles+ (via LIS)JAL 37,000 miles+ (via CMN)Economy, one way, estimate. Tap a connection for miles by cabin.

25 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.