Are there nonstop flights from Milan (MXP) to Denver (DEN)?

No. The fastest connection is via London, about 10h 55m of total flying time.

What is the fastest connection from Milan (MXP) to Denver (DEN)?

via London ≈ 10h 55m, via Reykjavík ≈ 11h 2m, via Frankfurt am Main ≈ 11h 6m (estimated flying time, excluding layovers).

from 27,500 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

Milan Malpensa International Airport (MXP) to Denver International Airport (DEN)・8,431 km

No nonstop flights. The fastest connection is via London (LHR), about 10h 55m of flying time (layover not included).

With milesANA 27,500 miles+ (via FRA)JAL 37,000 miles+ (via LHR)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

17 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.