Are there nonstop flights from New Orleans (MSY) to Panama City (PTY)?

No. The fastest connection is via Cancún, about 4h 4m of total flying time.

What is the fastest connection from New Orleans (MSY) to Panama City (PTY)?

via Cancún ≈ 4h 4m, via Tampa ≈ 4h 25m, via Miami ≈ 4h 28m (estimated flying time, excluding layovers).

from 15,000 JAL miles, from 30,000 ANA miles (economy, one way, based on the published award charts).

Louis Armstrong New Orleans International Airport (MSY) to Tocumen International Airport (PTY)・2,587 km

No nonstop flights. The fastest connection is via Cancún (CUN), about 4h 4m of flying time (layover not included).

With milesJAL 15,000 miles+ (via MIA)ANA 30,000 miles+ (via IAH)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

15 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.