Are there nonstop flights from Minneapolis (MSP) to Fort Myers (RSW)?

Yes. Southwest Airlines, Delta Air Lines, Frontier Airlines, Sun Country Airlines fly this route. Flight time is about 3h 11m.

What is the fastest connection from Minneapolis (MSP) to Fort Myers (RSW)?

via Nashville ≈ 3h 41m, via Atlanta ≈ 3h 42m, via St Louis ≈ 3h 42m (estimated flying time, excluding layovers).

from 15,000 JAL miles, from 15,000 ANA miles (economy, one way, based on the published award charts).

Minneapolis–Saint Paul International Airport / Wold–Chamberlain Field (MSP) to Southwest Florida International Airport (RSW)・2,282 km

Nonstop flights available (4 airlines). Flight time about 3h 11m. Nonstop return flights also operate.

With milesJAL 15,000 miles+ (via ORD)ANA 15,000 miles+ (via ORD)Economy, one way, estimate. Tap a connection for miles by cabin.

53 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.