Are there nonstop flights from Minneapolis (MSP) to Osaka (ITM)?

No. The fastest connection is via Tokyo, about 12h 47m of total flying time.

What is the fastest connection from Minneapolis (MSP) to Osaka (ITM)?

via Tokyo ≈ 12h 47m (estimated flying time, excluding layovers).

Minneapolis–Saint Paul International Airport / Wold–Chamberlain Field (MSP) to Osaka Itami International Airport (ITM)・9,892 km

No nonstop flights. The fastest connection is via Tokyo (HND), about 12h 47m of flying time (layover not included).

None.

1 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.