Are there nonstop flights from Madison (MSN) to San Francisco (SFO)?

No. The fastest connection is via Denver, about 4h 24m of total flying time.

What is the fastest connection from Madison (MSN) to San Francisco (SFO)?

via Denver ≈ 4h 24m, via Minneapolis ≈ 4h 26m, via Chicago ≈ 4h 41m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 23,000 JAL miles (economy, one way, based on the published award charts).

Dane County Regional Truax Field (MSN) to San Francisco International Airport (SFO)・2,845 km

No nonstop flights. The fastest connection is via Denver (DEN), about 4h 24m of flying time (layover not included).

With milesANA 15,000 miles+ (via DEN)JAL 23,000 miles+ (via PHX)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

17 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.