Are there nonstop flights from Madison (MSN) to Rome (FCO)?

No. The fastest connection is via Chicago, about 10h 18m of total flying time.

What is the fastest connection from Madison (MSN) to Rome (FCO)?

via Chicago ≈ 10h 18m, via Detroit ≈ 10h 19m, via Boston ≈ 10h 30m (estimated flying time, excluding layovers).

from 27,500 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

Dane County Regional Truax Field (MSN) to Rome–Fiumicino Leonardo da Vinci International Airport (FCO)・7,753 km

No nonstop flights. The fastest connection is via Chicago (ORD), about 10h 18m of flying time (layover not included).

With milesANA 27,500 miles+ (via ORD)JAL 37,000 miles+ (via CLT)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

12 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.