Are there nonstop flights from Manila (MNL) to Chicago (MDW)?

No. The fastest connection is via Seattle, about 16h 52m of total flying time.

What is the fastest connection from Manila (MNL) to Chicago (MDW)?

via Seattle ≈ 16h 52m, via San Francisco ≈ 17h 43m, via Los Angeles ≈ 18h 7m (estimated flying time, excluding layovers).

Ninoy Aquino International Airport (MNL) to Chicago Midway International Airport (MDW)・13,095 km

No nonstop flights. The fastest connection is via Seattle (SEA), about 16h 52m of flying time (layover not included).

None.

3 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.