Are there nonstop flights from Valletta (MLA) to Trapani (TPS)?

Yes. Ryanair fly this route. Flight time is about 51m.

Valletta → Trapani

Malta International Airport (MLA) to Vincenzo Florio Airport Trapani-Birgi (TPS)・291 km

Nonstop flights available (1 airline). Flight time about 51m. Nonstop return flights also operate.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.