Are there nonstop flights from Valletta (MLA) to Milan (MXP)?

Yes. Ryanair, easyJet fly this route. Flight time is about 1h 54m.

What is the fastest connection from Valletta (MLA) to Milan (MXP)?

via Palermo ≈ 2h 24m, via Rome ≈ 2h 25m, via Trapani ≈ 2h 25m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 15,000 JAL miles (economy, one way, based on the published award charts).

Malta International Airport (MLA) to Milan Malpensa International Airport (MXP)・1,191 km

Nonstop flights available (2 airlines). Flight time about 1h 54m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via ZRH)JAL 15,000 miles+ (via CDG)Economy, one way, estimate. Tap a connection for miles by cabin.

49 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.