Are there nonstop flights from Valletta (MLA) to London (LCY)?

No. The fastest connection is via Geneva, about 3h 27m of total flying time.

What is the fastest connection from Valletta (MLA) to London (LCY)?

via Geneva ≈ 3h 27m, via Nice ≈ 3h 27m, via Milan ≈ 3h 28m (estimated flying time, excluding layovers).

from 15,000 ANA miles (economy, one way, based on the published award charts).

Malta International Airport (MLA) to London City Airport (LCY)・2,084 km

No nonstop flights. The fastest connection is via Geneva (GVA), about 3h 27m of flying time (layover not included).

With milesANA 15,000 miles+ (via ZRH)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

16 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.