Are there nonstop flights from Valletta (MLA) to São Paulo (GRU)?

No. The fastest connection is via Barcelona, about 12h 46m of total flying time.

What is the fastest connection from Valletta (MLA) to São Paulo (GRU)?

via Barcelona ≈ 12h 46m, via Madrid ≈ 12h 48m, via Lisbon ≈ 12h 49m (estimated flying time, excluding layovers).

from 35,000 ANA miles, from 45,000 JAL miles (economy, one way, based on the published award charts).

Malta International Airport (MLA) to São Paulo/Guarulhos–Governor André Franco Montoro International Airport (GRU)・9,189 km

No nonstop flights. The fastest connection is via Barcelona (BCN), about 12h 46m of flying time (layover not included).

With milesANA 35,000 miles+ (via ZRH)JAL 45,000 miles+ (via CDG)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

17 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.