Are there nonstop flights from Medford (MFR) to Chicago (ORD)?

No. The fastest connection is via Salt Lake City, about 4h 27m of total flying time.

What is the fastest connection from Medford (MFR) to Chicago (ORD)?

via Salt Lake City ≈ 4h 27m, via Denver ≈ 4h 30m, via Portland ≈ 4h 42m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 15,000 JAL miles (economy, one way, based on the published award charts).

Rogue Valley International-Medford Airport (MFR) to Chicago O'Hare International Airport (ORD)・2,861 km

No nonstop flights. The fastest connection is via Salt Lake City (SLC), about 4h 27m of flying time (layover not included).

With milesANA 15,000 miles+ (via DEN)JAL 15,000 miles+ (via PDX)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

10 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.